Related Experiment Video
Updated: Jul 31, 2025

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
Published on: August 8, 2014
Granulomatous gingival manifestation in Melkersson Rosenthal syndrome: a case report
Mouna Snoussi1, Faten Frikha1, Hela Mnif2
1Department of Internal Medicine, Hedi Chaker Hospital, Medical School of Sfax, Sfax, Tunisia.
Abstract:
Melkersson-Rosenthal syndrome is a rare condition of unknown etiology. It is characterized by a classical triad of symptoms: relapsing facial and lip swelling, facial palsy and a fissured tongue. We report the case of a 29-year-old female patient who presented with the above-mentioned symptoms of Melkersson-Rosenthal syndrome. However, clinical examination revealed an exceptional manifestation, which is the gingival hyperplasia. The symptoms were partially managed with systemic steroids and surgical resection of gingival hyperplasia. The most significant finding to emerge from our case is that gingival enlargement can be identified as a rare clinical feature of the MRS disease, which is confirmed difficult to be managed.

