Related Experiment Video

Updated: Jul 31, 2025

Automated Analysis of Intracellular Phenotypes of Salmonella Using ImageJ
10:39

Automated Analysis of Intracellular Phenotypes of Salmonella Using ImageJ

Published on: August 9, 2022

2.9K

A Diagnostic Conundrum: Tuberculosis or Salmonella Neck Abscess?

Isaac Yieng Ler Tan1, Hardip Gendeh1, Marina Mat Baki1

  • 1Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.

Cureus
|May 9, 2023
PubMed

Insights

Granulomatous neck abscesses, typically from tuberculosis, can also be caused by Salmonella non-typhi (SN). This report highlights SN as a rare cause of neck granulomas, emphasizing broader differential diagnoses.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Pathology

Background:

  • Granulomatous neck abscesses are predominantly linked to Mycobacterium tuberculosis (TB).
  • Chronic inflammatory reactions manifesting as granulomas are infrequently associated with Salmonella non-typhi (SN) infections.

Observation:

  • Two poultry farmers presented with neck abscesses due to SN granulomas.
  • Tuberculosis polymerase chain reaction (PCR) tests were negative for both patients.
  • Histopathology revealed necrotizing granulomatous inflammation.

Findings:

  • Salmonella species are recognized to induce true granulomas in organs like bone marrow, liver, and spleen.
  • This case series describes, for the first time, true granulomas in cervical lymph nodes caused by SN.
  • The patients demonstrated recovery following surgical drainage and intravenous antibiotic therapy.

Implications:

  • Clinicians should consider non-tuberculous pathogens, such as Salmonella non-typhi, in the differential diagnosis of granulomatous neck abscesses.
  • This finding expands the understanding of Salmonella's potential to cause granulomatous inflammation in lymph nodes.
  • Early identification and appropriate antibiotic treatment are crucial for managing SN-induced granulomatous neck abscesses.
Keywords:
granulomainfectious disease pathologyneck abscesssalmonella nontyphituberculosis

More Related Videos

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos10:38

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos

Published on: September 9, 2015

10.5K
Loop-Mediated Isothermal Amplification for Screening Salmonella in Animal Food and Confirming Salmonella from Culture Isolation08:24

Loop-Mediated Isothermal Amplification for Screening Salmonella in Animal Food and Confirming Salmonella from Culture Isolation

Published on: May 20, 2020

8.2K

Related Concept Videos

Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
182
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
385