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Profile analysis of emerging respiratory virus in children
André Luís Elias Moreira1, Paulo Alex Neves da Silva1, Leandro do Prado Assunção2
1Microorganism Biotechnology Laboratory of Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, GO, Brazil.
Abstract:
Acute respiratory infections (ARIs) are caused by a variety of microorganisms. Of all ARIs, 80% are caused by viruses such as human respiratory syncytial virus, metapneumovirus, influenza, parainfluenza, rhinovirus, and, more recently, Sars-CoV-2, which has been responsible for the COVID-19 pandemic. The objective of our study was to evaluate clinical data from a viral panel performed in children hospitalized with SARS or COVID-19 in the infirmary or ICU of 5 pediatric hospitals in the city of Goiânia, Goiás, Brazil. Demographic, clinical, and laboratory data were collected for analysis, and data on the outcomes underwent statistical treatment. A total of 128 patients were selected for the study, 54% of whom were male and 46% female. The viral panel included rhinovirus, COVID-19, metapneumovirus, adenovirus, and parainfluenza. Descriptive analyses of age profile showed differences in the involvement of particular viruses. The percentage of patients who required hospitalization in the ICU, infirmary, as well as individuals who were discharged after therapy or who died, were described. Our work shows that epidemiological surveillance measures are indispensable, especially if used in the continued analysis of viral panels in all pediatric patients with SARS.
Insights
This study analyzed viral panels in children hospitalized with SARS or COVID-19 in Brazil. Epidemiological surveillance of viral infections in pediatric patients is crucial for public health.
Area of Science:
- Pediatric Infectious Diseases
- Virology
- Epidemiology
Background:
- Acute respiratory infections (ARIs) are predominantly viral, with SARS-CoV-2 causing the COVID-19 pandemic.
- A diverse range of viruses contribute to ARIs in children, necessitating comprehensive diagnostic approaches.
Purpose of the Study:
- To evaluate clinical data from viral panels in children hospitalized with SARS or COVID-19.
- To analyze demographic, clinical, and laboratory data associated with viral infections in pediatric patients.
Main Methods:
- Retrospective analysis of 128 pediatric patients hospitalized with SARS or COVID-19.
- Utilized a viral panel including rhinovirus, COVID-19, metapneumovirus, adenovirus, and parainfluenza.
- Collected and statistically analyzed demographic, clinical, and outcome data.
Main Results:
- The study included 128 pediatric patients (54% male, 46% female).
- Viral panel results showed varying age distributions for different viruses.
- Data on ICU admission, infirmary hospitalization, discharge, and mortality rates were described.
Conclusions:
- Epidemiological surveillance through continued analysis of viral panels is essential.
- This surveillance is particularly important for all pediatric patients presenting with SARS.
- Understanding viral epidemiology aids in managing pediatric respiratory infections.
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