Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Respiratory Assessment: Purpose and Indications

Respiratory Assessment: Purpose and Indications

Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...

Oxygen Transport in the Blood

Oxygen Transport in the Blood

Hemoglobin (Hb) is a crucial molecule in the human body, consisting of four polypeptide chains, each bound to an iron-containing heme group. This unique structure enables hemoglobin to bind to oxygen, with each molecule capable of combining with four molecules of oxygen, leading to rapid and reversible oxygen loading. When fully loaded with oxygen, it is called oxyhemoglobin, while hemoglobin that has released oxygen is called reduced hemoglobin or deoxyhemoglobin. As hemoglobin binds oxygen,...

Administering Oxygen by Mask

Administering Oxygen by Mask

Administering Oxygen by Mask
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:

Administering Oxygen by Nasal Cannula

Administering Oxygen by Nasal Cannula

Oxygen therapy is critical to patient care, especially for those struggling with respiratory issues. This intervention increases the oxygen concentration in the lungs, enhancing the amount of oxygen transported to the body's tissues. One standard method of delivering supplemental oxygen is through a nasal cannula, a non-invasive device that provides low to medium oxygen concentrations.
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils,...

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The interplay between organizational culture and burnout among ICU professionals: A cross-sectional multicenter study.

Journal of critical care·2024

Same author

Charting a new course in healthcare: early-stage AI algorithm registration to enhance trust and transparency.

NPJ digital medicine·2024

Same author

Ghrelin for Neuroprotection in Post-Cardiac Arrest Coma: A Randomized Clinical Trial.

JAMA neurology·2024

Same author

Conservative versus Liberal Oxygenation Targets in Intensive Care Unit Patients (ICONIC): A Randomized Clinical Trial.

American journal of respiratory and critical care medicine·2023

Same author

Early EEG monitoring predicts clinical outcome in patients with moderate to severe traumatic brain injury.

NeuroImage. Clinical·2023

Same author

Predicting responders to prone positioning in mechanically ventilated patients with COVID-19 using machine learning.

Annals of intensive care·2022

Search research articles

Related Experiment Video

Updated: Jul 31, 2025

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects

Published on: May 4, 2021

[Well-meant oxygen administration with harmful effects].

Walid Saleh^1,2, Alexander D Cornet¹

¹Medisch Spectrum Twente, afd. Intensive Care, Enschede.

Nederlands Tijdschrift Voor Geneeskunde

|May 10, 2023

Summary

Oxygen therapy, while vital for treating hypoxemia, can cause harm. High oxygen levels (hyperoxemia) lead to vasoconstriction and cell damage, increasing mortality and organ dysfunction, especially in surgery patients.

More Related Videos

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Published on: August 17, 2022

Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow

Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow

Published on: January 13, 2017

Related Experiment Videos

Last Updated: Jul 31, 2025

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects

Published on: May 4, 2021

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Published on: August 17, 2022

Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow

Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow

Published on: January 13, 2017

Area of Science:

Medical Science
Physiology
Emergency Medicine

Context:

Oxygen administration has a long history for treating hypoxemia.
Hyperoxemia, or excessive oxygen, can lead to adverse effects.
Harmful sequelae of hyperoxemia include vasoconstriction and reactive oxygen species formation.

Purpose:

To review the detrimental effects of hyperoxemia.
To highlight the pathophysiological mechanisms of hyperoxemia-induced damage.
To provide guidance on oxygen therapy targets in medical settings.

Summary:

Hyperoxemia causes vasoconstriction in coronary, cerebral, and systemic arteries.
It leads to reactive oxygen species, cellular damage, and cell death.
Clinical studies demonstrate increased mortality and organ dysfunction due to hyperoxemia in emergencies and surgery.

Impact:

Hyperoxemia increases mortality and organ dysfunction in various medical conditions.
The detrimental effects of hyperoxemia are also observed in patients undergoing elective surgery.
Normoxemia should be the target in most situations, with hyperoxemia justifiable only for short periods to prevent hypoxemia.