[Middle molecule level and myocardial contractility in kidney patients]

Myocardial contractility was studied in 50 patients, 30 of them in compensated stage and 20 with terminal chronic renal insufficiency via polycardiographic method, depending on the level of the substances with mean molecular weight in serum. No statistically significant changes in the parameters of polycardiogram were established in the patients with compensated renal function, nor in the level of "mean molecules" in serum, whereas a hypodynamic phase syndrome and energodynamic heart insufficiency were established in the terminal stage of chronic renal insufficiency, accompanied with significant increase of the level of the "mean molecules" in the serum of uremic patients.