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Genome-wide aggregated trans-effects on risk of type 1 diabetes: A test of the "omnigenic" sparse effector hypothesis

Andrii Iakovliev1, Stuart J McGurnaghan2, Caroline Hayward2

  • 1Usher Institute, College of Medicine and Veterinary Medicine, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, Scotland.

American Journal of Human Genetics
|May 10, 2023
PubMed

Keywords:
CTLA-4 antigenSTAT1 transcription factorT-lymphocytesautoimmune diseasescytokinesdiabetes mellitusforkhead transcription factorsgenome-wide association studykiller cellsnaturalquantitative trait lociregulatorytype 1

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