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Updated: Jul 31, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Desquamative Interstitial Pneumonia with Progressive Pulmonary Fibrosis
Takuhide Utsunomiya1, Yoshiaki Kinoshita1, Masayo Yoshimura2
1Department of Respiratory Medicine, Fukuoka University Chikushi Hospital, Japan.
Abstract:
A 70-year-old man who smoked was referred to our hospital because of progressive cough and dyspnea. Radiologic images showed ground-glass attenuation predominantly in the lower lung lobes. A surgical lung biopsy was performed, and a diagnosis of desquamative interstitial pneumonia (DIP) was made. The patient's symptoms improved with smoking cessation and steroid treatment, but the ground-glass attenuation did not completely resolve. At 10 years after the diagnosis, the fibrotic lesions deteriorated and treatment with nintedanib was subsequently initiated. Careful observation is needed in patients with DIP whose lung involvement does not completely improve with initial treatment.
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