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Updated: Aug 14, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Comparative studies on premedication and general anesthesia for endoscopies of the upper airways]
Abstract:
Cardiovascular disorders during endoscopy of the upper respiratory tract have since long induced anaesthetists and laryngologists to find a suitable anaesthetic procedure. It was the purpose of the present study to determine the influence exerted by different kinds of premedication and different modes of anaesthesia on the cardiovascular system, pO2, and the acid-base status. The results obtained show that a hypertensive-tachycardiac response to direct laryngo-tracheoscopy could not be prevented in any of the groups under investigation. Lowest blood pressure and heart rate increases were seen in those groups of patients which received an analgetic drug (Fentanyl or nitrous oxide) in addition to hexobarbital. During endoscopy, respiratory acidosis occurred in five groups of patients. All patients were sufficiently oxygenated.
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