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Published on: April 9, 2019
Quantitative MRI in the Local Staging of Prostate Cancer: A Systematic Review and Meta-Analysis
Vieley G Xiao1,2, Jordan Kresnanto2, Daniel A Moses3,4
1Medical Education, Faculty of Medicine and Health, University of New South Wales, Kensington, New South Wales, 2052, Australia.
Quantitative MRI markers show promise for detecting prostate cancer extracapsular extension (ECE). Tumor contact length (TCL) and apparent diffusion coefficient (ADC-mean) offer valuable diagnostic information for treatment planning.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Accurate local staging of prostate cancer (PCa) is crucial for effective treatment planning.
- Qualitative MRI interpretation for extracapsular extension (ECE) has limitations in sensitivity.
- Quantitative MRI techniques may improve the detection of ECE.
Conclusions:
- Both 10mm and 15mm thresholds for TCL are potentially suitable for clinical application in ECE detection.
- Apparent diffusion coefficient (ADC-mean) may offer superior performance compared to TCL at higher sensitivity levels.
- Quantitative MRI markers represent a valuable tool for improving the accuracy of local staging in prostate cancer.
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