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Updated: Jul 30, 2025

Intracerebroventricular Delivery of Gut-Derived Microbial Metabolites in Freely Moving Mice
Published on: June 2, 2022
The microbiota-gut-brain axis and neurodevelopmental disorders.
Qinwen Wang1,2, Qianyue Yang1,2, Xingyin Liu1,2,3,4
1State Key Laboratory of Reproductive Medicine and offspring Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
The gut microbiota influences brain function via the microbiota-gut-brain axis, impacting neurodevelopment. This review explores its role in neurodevelopmental disorders and future research directions.
Area of Science:
- Neuroscience
- Microbiology
- Developmental Biology
Background:
- The gut microbiota communicates with the brain via the microbiota-gut-brain axis.
- This axis regulates key physiological functions and is increasingly recognized for its role in neurodevelopment.
Conclusions:
- The microbiota-gut-brain axis is a critical factor in neurodevelopment and NDDs.
- Further research is needed to fully understand and therapeutically target this axis.
- Future directions include exploring novel interventions for NDDs based on microbiota modulation.
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