A 1,8-naphthimide-based Fluorescent Probe for Analyzing DMF/H₂O Composition

Area of Science:

• Analytical Chemistry
• Materials Science

Background:

• Accurate determination of N,N-dimethylformamide (DMF) in aqueous mixtures is crucial for environmental and industrial monitoring.
• Development of sensitive and selective fluorescent probes is essential for real-time chemical analysis.

Purpose of the Study:

• To design and synthesize a novel 1,8-naphthalimide-based fluorescent probe (BNAS) for quantifying DMF/deionized water (H2O) mixtures.
• To investigate the fluorescent response of BNAS to varying DMF concentrations.
• To evaluate the potential of BNAS as a portable sensor for DMF detection.

Main Methods:

• Synthesis of the 1,8-naphthalimide fluorescent probe (BNAS) incorporating a 2-thiopheneethylamine moiety.
• Spectroscopic analysis (fluorescence spectroscopy) to study the probe's response to DMF/H2O mixtures.
• Validation of the probe's linearity, selectivity, and sensitivity for DMF quantification.

Main Results:

• BNAS exhibited a distinct color change from dark to bright yellow-green with increasing DMF content.
• The fluorescence intensity of BNAS showed two linear relationships with DMF content (1-15% and 15-99%) at 535 nm.
• The probe demonstrated high selectivity and sensitivity for analyzing DMF/H2O mixtures across a wide volume ratio range (1/99 to 99/1).

Conclusions:

• BNAS is a highly effective fluorescent probe for the selective and sensitive determination of DMF in aqueous solutions.
• The probe's ability to be loaded onto filter paper enables the development of portable sensors for on-site DMF analysis.
• The study provides insights into the mechanism underlying the BNAS response to DMF/H2O composition.