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Updated: Jul 30, 2025

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
Published on: June 30, 2023
Outbreak report of SARS-CoV-2 infection by airborne transmission: Epidemiologic and molecular evidence
María-Cristina Navas1, Juan D Cerón2, Wbeimar Aguilar-Jiménez3
1Grupo Gastrohepatología, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia. biomedica@ins.gov.co.
Introduction:
It has been shown that the transmission of SARS-CoV-2 occurs mainly by air, and the risk of infection is greater in closed spaces.
Objective:
To describe the epidemiology, virology and molecular characterization of a COVID-19 outbreak at a closed vaccination point during the third wave of SARS-CoV-2 in Colombia.
Materials And Methods:
Diagnostic tests, interviews, sampling, cell cultures and viral sequencing were carried out, the latter being molecular characterization and lineage identification.
Results:
Seven workers were positive for SARS-CoV-2; among these, 3 samples were analyzed, plus an additional sample belonging to the mother of the presumed index case; all samples were identified with lineage B.1.625, with a maximum of 2 nucleotides difference between them.
Conclusions:
Variant B.1.625 was identified as the cause of the COVID-19 outbreak, and a co-worker was also identified as the index case. Unexpectedly, attending a vaccination day became a risk factor for acquiring the infection.
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