Related Experiment Video
Updated: Jul 30, 2025

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A Silicosis Mouse Model Established by Repeated Inhalation of Crystalline Silica Dust
Published on: January 6, 2023
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Skeletal Fluorosis in a Patient With Computer Cleaner Inhalant Abuse.
Evan Chen1, John Jayman2, Nora Bedrossian3
1Internal Medicine, Los Angeles County+University of Southern California (USC) Medical Center, Los Angeles, USA.
Cureus
|May 11, 2023
Summary
Skeletal fluorosis, a bone disease from excess fluoride, is increasingly seen in the US due to inhalant abuse. Early diagnosis via imaging and labs is key for treatment, which involves stopping substance use.
Area of Science:
- Toxicology
- Metabolic Bone Disease
- Radiology
Background:
- Skeletal fluorosis is a metabolic bone disease caused by excessive fluoride intake.
- Traditionally prevalent in developing nations, it's now emerging in the US linked to substance abuse.
- Recreational inhalant abuse is an under-recognized cause of fluoride toxicity.
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