Related Experiment Video

Updated: Jul 30, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.0K

Misdiagnosed Pityriasis Rubra Pilaris Successfully Managed With Isotretinoin: A Case Series

Nayla Al Khalifa1, Manal Alsabbagh1, Mazen Raees1

  • 1Dermatology, King Hamad University Hospital, Busaiteen, BHR.

Cureus
|May 11, 2023
PubMed

Insights

Diagnosing pityriasis rubra pilaris (PRP) is challenging, often mistaken for atopic dermatitis (AD). Dermoscopy and biopsy aid diagnosis, with Isotretinoin showing successful treatment outcomes for PRP.

Area of Science:

  • Dermatology
  • Rare Diseases
  • Inflammatory Dermatoses

Background:

  • Pityriasis rubra pilaris (PRP) is a rare inflammatory dermatosis.
  • Accurate diagnosis of PRP can be challenging for clinicians.
  • PRP is frequently misdiagnosed as atopic dermatitis (AD).

Observation:

  • This case series describes two patients with PRP initially diagnosed and treated as AD.
  • Patients were managed with topical corticosteroids for presumed AD.
  • Distinguishing features were noted upon further examination.

Findings:

  • Dermoscopy and biopsy are crucial tools for confirming PRP diagnosis.
  • Differentiating PRP from AD is essential for appropriate management.
  • Isotretinoin demonstrated successful treatment outcomes in these PRP cases.

Implications:

  • Improved diagnostic accuracy for PRP through dermoscopy and biopsy.
  • Timely and appropriate management of PRP can lead to better patient outcomes.
  • Isotretinoin is a viable and effective treatment option for pityriasis rubra pilaris.
Keywords:
atopic dermatitisisotretinoinkeratinizationpapulosquamous disorderspityriasis rubra pilaris

More Related Videos

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid04:12

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Published on: January 19, 2024

971
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.0K

Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
369
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.0K
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
219
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
11
Myocarditis IV: Nursing Management01:22

Myocarditis IV: Nursing Management

Myocarditis is an inflammatory condition of the myocardium requiring meticulous nursing management for optimal patient outcomes. Effective management begins with a thorough assessment of the patient's medical history, paying close attention to past infections, autoimmune disorders, travel history, and exposure to toxins or drugs. Recent viral infections and systemic diseases are particularly relevant due to their potential role in triggering myocarditis.Physical Examination and MonitoringThe...
13
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
119