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Updated: Jul 30, 2025

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Terminal bridging of siRNA duplex at the ribose 2' position controls strand bias and target sequence preference

Atsushi Shibata1, Hisao Shirohzu1,2, Yusuke Iwakami1

  • 1Division of R&D, Bonac Corporation, 1488-4 Aikawa, Kurume, Fukuoka 839-0861, Japan.

Molecular Therapy. Nucleic Acids
|May 11, 2023
PubMed

Keywords:
Dicer independentESB RNAMT: Oligonucleotides: Therapies and ApplicationsRNA interferencechemically bridged siRNAoff-target effectstrand biastarget sequence preference

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