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Updated: Jul 30, 2025

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Revision Anterior Cruciate Ligament Reconstruction (ACLR): Causes and How to Minimize Primary ACLR Failure
Lindsay C Roethke1,2, Jacob A Braaten1,2, Ariel N Rodriguez1,3
1Twin Cities Orthopedics, Edina-Crosstown, 4010 W 65th St, Edina, MN, 55435 USA.
Abstract:
Anterior cruciate ligament (ACL) tears are a common orthopaedic injury, particularly in athletic populations. Primary ACL reconstructions (ACLR) have fairly successful outcomes; however, there is a subset of patients who experience failure or re-injury and require a technically challenging revision ACLR procedure. Knowledge of the clinically relevant ACL anatomy and biomechanics, including closely associated meniscal, ligament, and osseous structures, is fundamental for an anatomic revision ACLR. Comprehensive evaluation and diagnosis are also critical to identify the causes of primary ACLR failure and determine appropriate treatment(s). Although outcomes have improved over time, revision ACLR patients still experience sub-optimal outcomes compared to primary ACLR patients. This review will highlight the current concepts of anatomy, biomechanics, clinical evaluation, treatment, outcomes, and post-operative rehabilitation to optimize outcomes for revision ACLR procedures.
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