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Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
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Chronic Diarrhea in an Infant With Malrotation: A Diagnostic Dilemma

Rohit Josyabhatla1, Nina Tatevian2, Amanda S Tchakarov2

  • 1From the Department of Pediatrics, Division of Pediatric Gastroenterology, UTHealth McGovern Medical School, Houston, TX.

JPGN Reports
|May 11, 2023
PubMed

Insights

Chronic diarrhea in infants presents diagnostic and management challenges. This case highlights complex evaluations for conditions beyond common causes like infections or cow milk protein intolerance.

Area of Science:

  • Pediatrics
  • Gastroenterology
  • Neonatal Medicine

Background:

  • Diarrhea is a major global health issue in children, particularly under 5 years.
  • Chronic diarrhea (lasting >2 weeks) in infants (<2 years) poses significant diagnostic and management difficulties.
  • Common causes include infectious enteritis and cow milk protein intolerance, but rarer conditions exist.

Keywords:
Clostridium difficile infectionchronic diarrheamalrotationsucrose deficiencyvery early onset inflammatory bowel disease

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