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Updated: Jul 30, 2025

Micropatterned Surfaces to Study Hyaluronic Acid Interactions with Cancer Cells
Published on: December 22, 2010
Hyaluronic Acid Basics and Rheology
Grace T Wu1, Joanna Kam2, Jason D Bloom3
1Department of Otorhinolaryngology, University of Pennsylvania, 3737 Market Street, Suite 302, Philadelphia, PA 19104, USA.
Abstract:
Hyaluronic acid (HA) is the most common dermal filler in use. It improves wrinkles and volume loss not only by filling and volumizing but also by hydrating the injected area with its water affinity. It is a naturally occurring component of skin, and there is a negligible risk of immunologic or allergic reaction with injection. It is rapidly degraded by the injection of hyaluronidase, thus creating an ideal injectable material that is low risk and reversible. Its duration of effect may be longer than expected based on bioavailability of the HA product due to collagen synthesis or fibroblast stimulation.
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