Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fragmented electrograms and continuous electrical activity in atrial flutter.

F G Cosio, F Arribas, J Palacios

    The American Journal of Cardiology
    |June 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Secondary haemophagocytic lymphohistiocytosis in COVID-19: correlation of the autopsy findings of bone marrow haemophagocytosis with HScore.

    Journal of clinical pathology·2021
    Same author

    Time-dependent cognitive and somatic symptoms of depression as predictors of new cardiac-related events in at-risk patients: the UPBEAT-UK cohort.

    Psychological medicine·2020
    Same author

    Mutational Screening of BRCA1/2 Genes as a Predictive Factor for Therapeutic Response in Epithelial Ovarian Cancer: A Consensus Guide from the Spanish Society of Pathology (SEAP-IAP) and the Spanish Society of Human Genetics (AEGH).

    Virchows Archiv : an international journal of pathology·2019
    Same author

    Recurrence quantification analysis with wavelet denoising and the characterization of magnetic flux emergence regions in solar photosphere.

    Physical review. E·2019
    Same author

    Modified SureSelect<sup>QXT</sup> Target Enrichment Protocol for Illumina Multiplexed Sequencing of FFPE Samples.

    Biological procedures online·2018
    Same author

    Air-Q<sup>®</sup> versus LMA Fastrach™ for fiberoptic-guided intubation: A randomized cross-over manikin trial.

    Revista espanola de anestesiologia y reanimacion·2017
    Same journal

    Real-World Effectiveness and Tolerability of Sacubitril/Valsartan in Octogenarian Patients With Heart Failure: Results From the PARACHUTER Study.

    The American journal of cardiology·2026
    Same journal

    ECG-Guided Conduction Pathways as a Lever to Shorten Post-TAVI Hospitalization.

    The American journal of cardiology·2026
    Same journal

    Cystatin-C versus creatinine and kidney function in heart failure with preserved ejection fraction: a SOGALDI-PEF analysis.

    The American journal of cardiology·2026
    Same journal

    Balloon-expandable versus Self-expanding Valves in Patients with Small Aortic Annuli Undergoing Transcatheter Aortic Valve Replacement.

    The American journal of cardiology·2026
    Same journal

    Drug-Coated Balloons versus Drug-Eluting Stents following Coronary Atherectomy in Severely Calcified Lesions: A Systematic Review and Meta-Analysis.

    The American journal of cardiology·2026
    Same journal

    Prehospital Statin Therapy and Outcomes in ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.

    The American journal of cardiology·2026
    See all related articles

    Fragmented electrograms are common in atrial flutter (AF), often within reentrant circuits. These abnormal electrical patterns in AF patients may indicate localized conduction issues.

    Area of Science:

    • Electrophysiology
    • Cardiology
    • Cardiac Arrhythmias

    Background:

    • Atrial flutter (AF) is a common supraventricular tachycardia.
    • Understanding the electrophysiological mechanisms of AF is crucial for effective treatment.

    Purpose of the Study:

    • To investigate the presence and characteristics of fragmented electrical activity in patients with atrial flutter.
    • To determine the relationship between fragmented electrograms and reentrant circuits in AF.

    Main Methods:

    • Recording multiple endocardial bipolar electrograms in 13 patients diagnosed with atrial flutter.
    • Analyzing electrogram fragmentation patterns, cycle length, and spatial distribution.
    • Assessing the correlation between fragmented areas and atrial activation pathways during flutter and stimulation.

    Related Experiment Videos

    Main Results:

    • Stable fragmentation patterns were observed in all 13 patients, occupying 36% to 100% of the flutter cycle.
    • Double or triple spike patterns were frequently noted.
    • Fragmented areas were often part of the atrial activation circuit, predominantly located in the right atrium.
    • Changes in fragmented electrograms correlated with AF pattern modifications during stimulation and disappeared upon restoration of sinus rhythm.

    Conclusions:

    • Fragmented electrograms are a frequent finding in atrial flutter.
    • These findings suggest a link between fragmented electrograms, abnormal local conduction, and the reentrant circuits responsible for atrial flutter.