Decreasing Bilirubin Serum Tests in Healthy Newborns During Birth Hospitalization

Sarah Sukkar1, Gabriella Lorusso1, Sara Jananeh1

  • 1Holtz Children's Hospital at Jackson Memorial Hospital, Miami, Florida.

Pediatrics
|May 12, 2023
PubMed

Insights

Value-care interventions significantly reduced total serum bilirubin (TSB) testing in healthy newborns by 48%, decreasing unnecessary testing without causing harm. This quality improvement initiative improved newborn care efficiency.

Area of Science:

  • Neonatal Medicine
  • Quality Improvement Science
  • Healthcare Management

Background:

  • Variability in hyperbilirubinemia screening and monitoring leads to excessive total serum bilirubin (TSB) testing in healthy newborns.
  • Current practices often involve unnecessary TSB testing due to fear of hyperbilirubinemia and varied clinical judgment.

Purpose of the Study:

  • To assess the impact of value-care interventions on reducing the monthly TSB testing rate per 100 patient-days in healthy newborns.
  • To achieve a 30% decrease in monthly TSB testing by June 2022.

Main Methods:

  • A multidisciplinary team reviewed current TSB ordering practices in a Mother-Baby Unit.
  • Interventions included faculty engagement, pathway redesign, staff education on high-value care, an instructional video, and EHR-integrated bilirubin risk assessment prompts.
  • Primary outcome: monthly TSB testing rate per 100 patient-days; balancing measures: predischarge screening, length of stay, phototherapy, and readmission rates.

Main Results:

  • The monthly TSB testing rate decreased by 48%, from 51 to 26.3 TSB per 100 patient-days, with sustained improvement for 12 months.
  • The percentage of infants with at least one TSB measurement during hospitalization dropped from 48% to 30%.
  • Predischarge bilirubin screening, length of stay, and readmission rates remained unchanged.

Conclusions:

  • A quality improvement initiative successfully reduced TSB testing in healthy newborns.
  • The interventions led to a significant decrease in testing rates without evidence of harm to patients.
  • Value-care strategies can optimize neonatal hyperbilirubinemia management.
Abstract

Related Concept Videos

Serum Studies: Renal Function Tests01:24

Serum Studies: Renal Function Tests

Renal function tests are crucial for assessing kidney health, monitoring disease progression, and evaluating the kidneys' efficiency in waste elimination, fluid balance, and electrolyte regulation. These tests offer critical insights into kidney function, even though routine measurements may appear normal until there is a significant decline in the glomerular filtration rate or GFR. Typically, signs of kidney impairment only become evident when the GFR falls to about 50% of its normal level.
25
Transcytosis of IgG01:15

Transcytosis of IgG

Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
2.8K
Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
379
Rh Blood Group01:19

Rh Blood Group

The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
1.6K
Lifecycle of Erythrocytes01:22

Lifecycle of Erythrocytes

Erythrocytes, also known as red blood cells, constantly move through blood capillaries. As a result, they damage their plasma membrane due to the continuous friction. Typically, after 100 to 120 days, erythrocytes become rigid and fragile as they wear out. As they pass through small vessels in the spleen and liver, they can get trapped and break apart into fragments.
The resident phagocytic macrophages deal with these damaged cells by engulfing them and separating their globin and heme groups....
2.0K