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Updated: Jul 30, 2025

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
NET-Works paediatric obesity prevention trial: 66 month outcomes
Simone A French1, Alicia S Kunin-Batson2, Nancy E Sherwood1
1Division of Epidemiology & Community Health, University of Minnesota School of Public Health, Minneapolis, Minnesota, USA.
Insights
The NET-Works trial found a 3-year obesity prevention intervention did not significantly reduce overall child BMI at 66 months. However, it slowed BMI gain in overweight and Hispanic children, suggesting targeted early interventions are effective.
Area of Science:
- Pediatric obesity prevention
- Public health interventions
- Childhood cardiometabolic health
Background:
- The NET-Works trial (2012-2018) evaluated a multicomponent obesity prevention intervention for children aged 2-4 years.
- The study aimed to assess long-term effects on body mass index (BMI) and related factors.
Purpose of the Study:
- To examine the 66-month treatment effects of a multicomponent obesity prevention intervention on child BMI and other health outcomes.
- To identify potential subgroup effects within the intervention and control groups.
Main Methods:
- Randomized controlled trial involving 534 children and their caregivers.
- Follow-up measurements at 66 months included child BMI, physical activity, diet, and cardiometabolic risk factors for 338 parent-child dyads.
Main Results:
- No significant overall treatment effect on child BMI was observed at 66 months (Effect = -0.38).
- The intervention significantly slowed BMI gain in children who were overweight at baseline (Effect = -1.28).
- Hispanic children in the intervention group showed significantly less BMI gain compared to the control group (Effect = -1.04).
Conclusions:
- Community-based, multicomponent interventions may effectively reduce excess weight gain in specific high-risk subgroups.
- The NET-Works intervention demonstrated effectiveness in slowing BMI gain among overweight and Hispanic children at 66 months post-randomization.
Background And Objectives:
The NET-Works trial (2012-2018) randomized 534 children ages 2-4 years at baseline and their caregivers to either a 3-year multicomponent obesity prevention intervention or a control group. This research examined treatment effects on body mass index and other outcomes at 66 months.
Methods:
Parent-child dyads (n = 338) who agreed to participate in a 66 month measurement visit were measured for child BMI, physical activity, diet, and cardiometabolic risk factor variables.
Results:
At 66 months, no significant treatment effects were observed on BMI (Effect = -0.38; 95% CI = -1.13, 0.37). Subgroup results were consistent with the NET-Works 36 month results. Children with overweight at baseline in the intervention group gained significantly less BMI versus children with overweight in the control group (Effect = -1.28; 95% CI = -2.48, -0.07). Among Hispanic children, those in the intervention gained significantly less BMI than those in the control group (Effect = -1.04; 95% CI = -1.97, -0.11).
Conclusions:
Evidence suggests that early intervention with children at highest risk for obesity, using community-based, multicomponent, multisetting interventions, may be effective in reducing excess weight gain and obesity among certain subgroups of children. The intervention appeared to be effective in slowing BMI gain 66 months after randomization among children who were already overweight at ages 2-4 years and among children of Hispanic ethnicity.
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