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Published on: October 31, 2012
High-throughput Sequencing to Identify Bacteremia in Children with Cancer
Son H McLaren1, Nischay Mishra2, Nobuko Hijiya3
1From the Division of Pediatric Emergency Medicine, Department of Emergency Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY.
Abstract:
Current methods to diagnose bacteremia are limited. In this pilot study of children with cancer presenting with fever, we determined the concordance between a novel high-throughput sequencing platform called BacCapSeq and blood culture. High-throughput sequencing had modest concordance with blood culture. Discordant organisms included those with both unlikely or potential clinical relevance.
