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Updated: Jul 30, 2025
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Simultaneous Visualization of the Dynamics of Crosslinked and Single Microtubules In Vitro by TIRF Microscopy
Published on: February 18, 2022
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Microtubules and viral infection
Eveline Santos da Silva1, Mojgan H Naghavi2
1Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States; HIV Clinical and Translational Research, Luxembourg Institute of Health, Department of Infection and Immunity, Esch-sur-Alzette, Luxembourg.
Advances in Virus Research
|May 12, 2023
Summary
Microtubules (MTs) are vital for cell structure and transport. Viruses exploit these cellular highways and their regulatory proteins for replication within diverse cellular compartments.
Area of Science:
- Cell Biology
- Virology
- Cytoskeleton Dynamics
Background:
- Microtubules (MTs) are dynamic intracellular filaments crucial for cellular structure, motility, division, and intracellular transport.
- Specialized proteins regulate MT nucleation, growth, stability, and cargo transport, ensuring precise cellular organization.
Conclusions:
- Understanding MT-virus interactions is critical for deciphering viral pathogenesis.
- Targeting MT networks presents potential avenues for antiviral therapeutic strategies.
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