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Updated: Jul 30, 2025

Histological Quantification of Chronic Myocardial Infarct in Rats
Published on: December 11, 2016
Chronic or Changeable Infarct Size after Spontaneous Coronary Artery Dissection
Gordana Krljanac1, Svetlana Apostolovic2, Zlatko Mehmedbegovic1
1University Clinical Center of Serbia, Cariology Clinic, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Abstract:
Spontaneous coronary artery dissection (SCAD) could be the cause of acute myocardial infarction (AMI) and sudden cardiac death. Clinical presentations can vary considerably, but the most common is the elevation of cardiac biomarkers associated with chest discomfort. Different pathological etiology in comparison with Type 1 AMI is the underlying infarct size in this population. A 42-year-old previously healthy woman presented with SCAD. Detailed diagnostical processing and treatment which were performed could not prevent myocardial injury. The catheterization laboratory was the initial place for the establishment of a diagnosis and proper management. The management process can be very fast and sometimes additional imaging methods are necessary. Finding predictors of SCAD recurrence is challenging, as well as predictors of the resulting infarct scar size. Patients with recurrent clinical symptoms of chest pain, ST elevation, and complication represent a special group of interest. Therapeutic approaches for SCAD range from the "watch and wait" method to complete revascularization with the implantation of one or more stents or aortocoronary bypass grafting. The infarct size could be balanced through the correct therapeutical approach, and, proper multimodality imaging would be helpful in the assessment of infarct size.
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