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Bullous morphea profunda.

W P Su, S L Greene

    The American Journal of Dermatopathology
    |April 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Morphea profunda, a deep sclerotic skin condition, presented in a 58-year-old man. Histology confirmed deep dermal and fascial sclerosis, distinguishing it from eosinophilic fasciitis.

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    Area of Science:

    • Dermatology
    • Pathology

    Background:

    • Eosinophilic fasciitis and morphea profunda are deep sclerotic skin conditions.
    • Clinical presentation can be similar, necessitating detailed histopathological analysis.

    Observation:

    • A 58-year-old male developed deep sclerotic plaques on his shins, initially suspected as eosinophilic fasciitis or morphea profunda.
    • Subsequent development of bullae and skin biopsy revealed deep dermal, pannicular, and fascial sclerosis with subepidermal edema.
    • Typical morphea plaques later appeared on the penis, and no systemic abnormalities were noted.

    Findings:

    • Histopathology demonstrated sclerosis and inflammation extending beyond the fascia, with subepidermal edema causing bullae formation.
    • Absence of vasculitis, lymphatic obstruction, peripheral eosinophilia, or hypergammaglobulinemia.

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  • The deeper sclerotic process involving more than fascia supports the diagnosis of morphea profunda over eosinophilic fasciitis.

    • Implications:

    • The term "morphea profunda" is proposed as more accurate for this deeper variant of morphea.
    • Distinguishing morphea profunda from eosinophilic fasciitis is crucial for appropriate diagnosis and management.
    • This case highlights the importance of histopathology in differentiating deep sclerotic skin diseases.