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Related Experiment Video

Updated: Jul 30, 2025

Printing Thermoresponsive Reverse Molds for the Creation of Patterned Two-component Hydrogels for 3D Cell Culture
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Hydrogels for Oral Tissue Engineering: Challenges and Opportunities.

Anfu Chen1,2, Shuhua Deng1, Jindi Lai1

  • 1Guangdong Provincial Key Laboratory of Functional Soft Condensed Matter, School of Materials and Energy, Guangdong University of Technology, Guangzhou 510006, China.

Molecules (Basel, Switzerland)
|May 13, 2023
PubMed
Summary

Hydrogels show promise for oral tissue engineering, aiding in fighting infections and promoting tissue growth for dental applications. Further research is needed to overcome challenges for successful clinical use.

Keywords:
dental pulphydrogelsmandibleperiodontiumtissue engineering

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Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Dental Research

Background:

  • Oral diseases are prevalent globally, necessitating advanced dental biomaterials.
  • Oral tissue engineering requires strategies for both infection control and tissue regeneration.

Purpose of the Study:

  • To review hydrogel classifications (natural and synthetic) for dental applications.
  • To discuss current hydrogel applications in endodontic, periodontal, and soft tissue restorations.
  • To explore antimicrobial and tissue growth promotion strategies within hydrogel-based dental treatments.

Main Methods:

  • Literature review of hydrogels in oral tissue engineering.
  • Classification of natural and synthetic hydrogels.
  • Analysis of hydrogel applications in various dental restoration areas.

Main Results:

  • Hydrogels are versatile biomaterials for oral tissue regeneration and drug delivery.
  • Applications span endodontic, periodontal, and soft tissue restorations.
  • Various antimicrobial and growth-promoting strategies are integrated into dental hydrogels.

Conclusions:

  • Hydrogels offer significant potential in oral tissue engineering.
  • Challenges remain in achieving optimal clinical outcomes.
  • Future developments are needed to address current limitations in dental hydrogel applications.