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Topical Treatment for Retinal Degenerative Pathologies: A Systematic Review
Lăcrămioara Samoilă1, Oliviu Voștinaru2, Elena Dinte3
1Department of Physiology, "Iuliu Hatieganu" University of Medicine & Pharmacy, 400006 Cluj-Napoca, Romania.
International Journal of Molecular Sciences
|May 13, 2023
Summary
Topical ocular drug delivery faces challenges reaching the retina. Advanced formulations show promise for treating retinal degenerative diseases, improving drug efficacy and patient outcomes.
Area of Science:
- Ophthalmology
- Pharmaceutics
- Drug Delivery
Background:
- Topical administration is preferred for ocular therapy, but eye barriers limit drug penetration to retinal structures.
- Retinal degenerative diseases require effective drug delivery to the posterior eye segment.
Conclusions:
- Effective topical drug delivery to the retina remains a significant challenge.
- Novel formulation strategies are crucial for developing predictable and controlled drug delivery to the posterior eye.
- Future advancements hold potential for more effective treatments for retinal degenerative diseases.
