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A Metabolomics and Big Data Approach to Cannabis Authenticity (Authentomics).

Pramodkumar D Jadhav1, Youn Young Shim1,2,3, Ock Jin Paek4

  • 1Department of Food and Bioproduct Sciences, University of Saskatchewan, Saskatoon, SK S7N 5A8, Canada.

International Journal of Molecular Sciences
|May 13, 2023
PubMed
Summary

Authentic cannabis product verification requires advanced analytical methods. This study introduces authentomics, combining non-targeted metabolomics with big data, to ensure cannabis quality and meet ISO standards.

Keywords:
Cannabis sativa L. authentomicsNMRcannabis authenticitymetabolites

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Area of Science:

  • Agricultural Chemistry
  • Analytical Chemistry
  • Biotechnology

Background:

  • Cannabis (Cannabis sativa L.) products are increasingly accessible for recreational and therapeutic use.
  • Regulatory bodies require robust methods to ensure the safety and efficacy of cannabis products.
  • Current targeted analyses are insufficient for the metabolic complexity of cannabis.

Purpose of the Study:

  • To review the authentomics of cannabis for quality verification.
  • To explore the potential of authentomics in meeting International Organization for Standardization (ISO) standards.
  • To highlight the necessity of non-targeted metabolomic analysis for comprehensive cannabis profiling.

Main Methods:

  • Non-targeted metabolomic analysis of cannabis products.
  • An authentomics approach combining new sample analysis with historical authenticated datasets.
  • Development of an integrated database for cannabis analytical results.

Main Results:

  • Authentomics offers a robust method for verifying cannabis product quality.
  • Non-targeted analysis is crucial for understanding cannabis metabolic complexity.
  • The authentomics platform technology is essential for meeting ISO standards.

Conclusions:

  • Authentomics is a promising approach for ensuring cannabis product authenticity and quality.
  • Implementing authentomics and an integrated database can help meet ISO standards for cannabis analysis.
  • This review is the first to address the authentomics of cannabis and its regulatory implications.