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At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
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Related Experiment Video

Updated: Jul 30, 2025

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
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Factors Associated with Visual Acuity in Advanced Glaucoma.

Hyun Jee Kim1, Mi Sun Sung1, Sang Woo Park1

  • 1Department of Ophthalmology, Research Institute of Medical Sciences, Chonnam National University Medical School and Hospital, Gwangju 61469, Republic of Korea.

Journal of Clinical Medicine
|May 13, 2023
PubMed
Summary

Subfoveal choroidal thickness and central visual field sensitivity, particularly in the inferior area, significantly impact best-corrected visual acuity in advanced glaucoma patients. These factors are crucial for understanding vision loss in this condition.

Keywords:
advanced glaucomacentral visual fieldsubfoveal choroidal thicknessvisual acuity

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Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Visual Neuroscience

Background:

  • Advanced glaucoma leads to significant vision loss, impacting best-corrected visual acuity (BCVA).
  • Identifying factors affecting BCVA is crucial for managing advanced glaucoma patients.

Purpose of the Study:

  • To comprehensively analyze parameters influencing BCVA in advanced glaucoma.
  • To determine the correlation between ocular structural measurements and visual field parameters with BCVA.

Main Methods:

  • Retrospective cross-sectional study of 113 advanced glaucoma patients.
  • Spectralis optical coherence tomography (OCT) for retinal nerve fiber layer (RNFL) and macular thickness measurements.
  • Pearson correlation and multivariate regression analyses to assess associations with BCVA.

Main Results:

  • Peripapillary RNFL thickness, subfoveal choroidal thickness, and macular thickness (RNFL, GCL, IPL) correlated with BCVA.
  • Multivariate analysis identified subfoveal choroidal thickness and central visual field mean sensitivity (especially inferior hemifield) as significant factors affecting BCVA.

Conclusions:

  • Subfoveal choroidal thickness is a key factor influencing BCVA in advanced glaucoma.
  • Central visual field sensitivity, particularly in the inferior hemifield, is significantly related to BCVA in this patient group.