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Hypertensive Heart Disease-The Imaging Perspective
Tevfik F Ismail1, Simon Frey2, Beat A Kaufmann2
1King's College London & Cardiology Department, School of Biomedical Engineering and Imaging Sciences, Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK.
Insights
Hypertensive heart disease (HHD) involves structural and functional changes in the heart due to high blood pressure. This review highlights multimodality imaging for diagnosing HHD and differentiating it from other conditions.
Area of Science:
- Cardiology
- Hypertension Research
- Medical Imaging
Background:
- Hypertensive heart disease (HHD) results from prolonged elevated systemic blood pressure affecting cardiac structures.
- Chronic hypertension leads to left ventricular hypertrophy, interstitial fibrosis, diastolic dysfunction, and impaired atrial/ventricular mechanics.
- These cardiac alterations can progress to heart failure with preserved (HFpEF) or reduced (HFrEF) ejection fraction.
Purpose of the Study:
- To review the clinical evaluation of patients with hypertension and suspected HHD.
- To emphasize the role and recent advancements in multimodality imaging for HHD diagnosis.
- To discuss the use of imaging in the differential diagnosis of HHD.
Main Methods:
- Review of clinical evaluation strategies for hypertension and HHD.
- Analysis of recent advancements in multimodality cardiovascular imaging techniques.
- Discussion of imaging findings in the context of HHD pathophysiology.
Main Results:
- Multimodality imaging plays a crucial role in diagnosing HHD.
- Recent imaging advances enhance the detection of subtle structural and functional cardiac changes.
- Imaging aids in differentiating HHD from other causes of cardiac dysfunction.
Conclusions:
- Accurate diagnosis of HHD relies on integrating clinical assessment with advanced imaging.
- Multimodality imaging is essential for identifying cardiac remodeling and dysfunction caused by hypertension.
- Imaging facilitates timely and accurate differential diagnosis, guiding appropriate patient management.
Abstract:
Hypertensive heart disease (HHD) develops in response to the chronic exposure of the left ventricle and left atrium to elevated systemic blood pressure. Left ventricular structural changes include hypertrophy and interstitial fibrosis that in turn lead to functional changes including diastolic dysfunction and impaired left atrial and LV mechanical function. Ultimately, these changes can lead to heart failure with a preserved (HFpEF) or reduced (HFrEF) ejection fraction. This review will outline the clinical evaluation of a patient with hypertension and/or suspected HHD, with a particular emphasis on the role and recent advances of multimodality imaging in both diagnosis and differential diagnosis.
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