Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hydroboration-Oxidation of Alkenes03:08

Hydroboration-Oxidation of Alkenes

8.5K
In addition to the oxymercuration–demercuration method, which converts the alkenes to alcohols with Markovnikov orientation, a complementary hydroboration-oxidation method yields the anti-Markovnikov product. The hydroboration reaction, discovered in 1959 by H.C. Brown, involves the addition of a B–H bond of borane to an alkene giving an organoborane intermediate. The oxidation of this intermediate with basic hydrogen peroxide forms an alcohol.
8.5K
Reactions of Aldehydes and Ketones: Baeyer–Villiger Oxidation01:22

Reactions of Aldehydes and Ketones: Baeyer–Villiger Oxidation

4.2K
Baeyer–Villiger oxidation converts aldehydes to carboxylic acids and ketones to esters. The reaction uses peroxy acids or peracids and is often catalyzed by acid. The reaction is named after its pioneers, Adolf von Baeyer and Victor Villiger. The reaction is achieved by a wide range of peracids such as m-chloroperoxybenzoic acid (mCPBA), perbenzoic acid (C6H5COOOH), peracetic acid (CH3COOOH), hydrogen peroxide (H2O2), and tert-butyl hydroperoxide (t-BuOOH).
The carbonyl center is...
4.2K
Oxidative Cleavage of Alkenes: Ozonolysis01:46

Oxidative Cleavage of Alkenes: Ozonolysis

10.7K
In ozonolysis, ozone is used to cleave a carbon–carbon double bond to form aldehydes and ketones, or carboxylic acids, depending on the work-up.
Ozone is a symmetrical bent molecule stabilized by a resonance structure.
10.7K
Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)00:53

Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)

2.0K
Acyclic diene metathesis polymerization or ADMET polymerization involves cross-metathesis of terminal dienes, such as 1,8-nonadiene, to give linear unsaturated polymer and ethylene. As ADMET is a reversible process, the formed ethylene gas must be removed from the reaction mixture to complete the polymerization process.
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
2.0K
Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation02:47

Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation

18.4K
Introduction
One of the convenient methods for the preparation of aldehydes and ketones is via hydration of alkynes. Hydroboration-oxidation of alkynes is an indirect hydration reaction in which an alkyne is treated with borane followed by oxidation with alkaline peroxide to form an enol that rapidly converts into an aldehyde or a ketone. Terminal alkynes form aldehydes, whereas internal alkynes give ketones as the final product.
18.4K
Oxidation and Reduction of Organic Molecules01:19

Oxidation and Reduction of Organic Molecules

6.8K
Energy production within a cell involves many coordinated chemical pathways. Most of these pathways are combinations of oxidation and reduction reactions, which occur at the same time. An oxidation reaction strips an electron from an atom in a compound, and the addition of this electron to another compound is a reduction reaction. Because oxidation and reduction usually occur together, these pairs of reactions are called redox reactions.
The removal of an electron from a molecule, results in a...
6.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pediatric Firearm Trauma on the Rise: A Retrospective Review of Over 1,100 Cases in 12 Years at One Center.

Journal of pediatric surgery·2024
Same author

Synthesis and Evaluation of Cereblon-Recruiting HaloPROTACs.

Chembiochem : a European journal of chemical biology·2023
Same author

Computational Exploration of Potential CFTR Binding Sites for Type I Corrector Drugs.

Biochemistry·2023
Same author

Nitrile Oxidation at a Ruthenium Complex leading to Intermolecular Imido Group Transfer.

Organometallics·2021
Same author

Diastereoselective Synthesis of Terminal Bromo-Substituted Propargylamines via Generation of Lithium Bromoacetylide and Addition to Chiral <i>N</i>-<i>tert</i>-Butanesulfinyl Aldimines.

The Journal of organic chemistry·2021
Same author

Structural Consequences of the 1,2,3-Triazole as an Amide Bioisostere in Analogues of the Cystic Fibrosis Drugs VX-809 and VX-770.

ChemMedChem·2020

Related Experiment Video

Updated: Jul 30, 2025

Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase
10:14

Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase

Published on: November 8, 2019

6.4K

A Biodegradable, Polymer-Supported Oxygen Atom Transfer Reagent.

Erin E Ramey1, Elizabeth L Whitman2, Cole E Buller1

  • 1Department of Chemistry and Biochemistry, Hope College, Holland, MI 49422, USA.

Polymers
|May 13, 2023
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel biodegradable polymer with a built-in oxygen atom transfer capability. This innovation offers a sustainable solution for chemical synthesis, reducing plastic waste and environmental impact.

Keywords:
biodegradable polymersorganocatalytic ring-opening polymerizationoxygen atom transfer

More Related Videos

Atom Transfer Radical Polymerization of Functionalized Vinyl Monomers Using Perylene as a Visible Light Photocatalyst
06:49

Atom Transfer Radical Polymerization of Functionalized Vinyl Monomers Using Perylene as a Visible Light Photocatalyst

Published on: April 22, 2016

11.9K
Optimization of Radiochemical Reactions using Droplet Arrays
10:54

Optimization of Radiochemical Reactions using Droplet Arrays

Published on: February 12, 2021

3.5K

Related Experiment Videos

Last Updated: Jul 30, 2025

Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase
10:14

Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase

Published on: November 8, 2019

6.4K
Atom Transfer Radical Polymerization of Functionalized Vinyl Monomers Using Perylene as a Visible Light Photocatalyst
06:49

Atom Transfer Radical Polymerization of Functionalized Vinyl Monomers Using Perylene as a Visible Light Photocatalyst

Published on: April 22, 2016

11.9K
Optimization of Radiochemical Reactions using Droplet Arrays
10:54

Optimization of Radiochemical Reactions using Droplet Arrays

Published on: February 12, 2021

3.5K

Area of Science:

  • Polymer Chemistry
  • Organic Synthesis
  • Materials Science

Background:

  • Biodegradable polymers are crucial for reducing plastic waste.
  • Organocatalytic ring-opening polymerization (OROP) enables the synthesis of diverse biodegradable polymers.
  • Functionalizing polymer backbones with reactive groups is an active area of research.

Purpose of the Study:

  • To report the first instance of an oxygen atom transfer reagent integrated into a biodegradable polymer backbone.
  • To synthesize a novel biodegradable polycarbonate functionalized for oxygen atom transfer.
  • To demonstrate the reactivity of the synthesized polymer-supported reagent.

Main Methods:

  • Synthesis of a cyclic monomer from 2,2-bis(hydroxymethyl) propionic acid.
  • Organocatalytic ring-opening polymerization (OROP) to create the polycarbonate backbone.
  • Post-polymerization modification to introduce an iodosylaryl group.
  • X-ray photoelectron spectroscopy (XPS) for characterizing the I-O bond.
  • Oxygen atom transfer reaction with triphenylphosphine as a model substrate.

Main Results:

  • Successful synthesis of a biodegradable polycarbonate with a pendant iodoaryl group.
  • Characterization of the key iodine-oxygen (I-O) bond using XPS spectroscopy.
  • Demonstration of the polymer's ability to perform oxygen atom transfer to triphenylphosphine.

Conclusions:

  • A novel biodegradable polymer featuring an oxygen atom transfer reagent has been successfully synthesized and characterized.
  • This work presents a new platform for developing functional biodegradable materials for catalytic applications.
  • The polymer-supported reagent offers a promising avenue for sustainable chemical transformations.