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Related Experiment Video

Updated: Jul 30, 2025

Fused Filament Fabrication FFF of Metal-Ceramic Components
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Preparation of Polylactic Acid/Calcium Peroxide Composite Filaments for Fused Deposition Modelling.

Abdullah H Mohammed1,2, Nikolina Kovacev1, Amr Elshaer3

  • 1School of Engineering, University of Birmingham, Birmingham B15 2TT, UK.

Polymers
|May 13, 2023
PubMed
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Review on Engineering of Bone Scaffolds Using Conventional and Additive Manufacturing Technologies.

3D printing and additive manufacturing·2024

Researchers developed a new polylactic acid (PLA)/calcium peroxide (CPO) composite filament for 3D printing. The 6% CPO filament showed promising printability and mechanical properties for biomedical applications.

Area of Science:

  • Biomaterials Science
  • Polymer Engineering
  • Additive Manufacturing

Background:

  • Fused Deposition Modelling (FDM) 3D printing is increasingly used in pharmaceutical and biomedical fields.
  • Development of novel biocompatible filaments is crucial for advancing FDM applications in medicine.

Purpose of the Study:

  • To develop and characterize a new polylactic acid (PLA)/calcium peroxide (CPO) composite filament for FDM 3D printing.
  • To evaluate the printability and properties of the developed composite for potential biomedical uses.

Main Methods:

  • Composite filaments were fabricated using wet solution mixing and extrusion with varying CPO content (3-24% wt.).
  • Filaments were characterized for microstructure, rheology, mechanical properties, and surface morphology.
  • Printability testing was performed on selected filaments, including the fabrication of a bone scaffold.
Keywords:
3D printingFDM filamentsbiomedical filamentcalcium peroxidecomposite filamentspolylactic acid

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Main Results:

  • Increasing CPO content raised viscosity and shifted PLA/CPO microstructures from crystalline to amorphous.
  • Mechanical strength and ductility generally decreased with higher CPO, except for the 6% CPO filament.
  • The 6% CPO PLA/CPO filament demonstrated acceptable surface morphology, strength, and good print quality for a bone scaffold.

Conclusions:

  • The developed PLA/CPO composite filament, particularly at 6% CPO, shows potential as an improved biocompatible material for FDM 3D printing.
  • This material could be beneficial for creating customized biomedical devices and scaffolds.