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Fortuitous somatic mutations during antibody evolution endow broad neutralization against SARS-CoV-2 Omicron variants

Jianbo Wu1, Zhenguo Chen1, Yidan Gao1

  • 1Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, Shanghai Frontiers Science Center of Pathogenic Microbes and Infection, Shanghai Fifth People's Hospital, Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, School of Public Health, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.

Cell Reports
|May 13, 2023
PubMed

Keywords:
CP: ImmunologyCP: MicrobiologySARS-CoV-2bNAbbroadly neutralizing antibodyclonally related antibody familysomatic hypermutationvariant of concern

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