[Clinical study of HCFU and radiation therapy in head and neck cancer]

We have investigated the usefulness of combination therapy of HCFU with radiation by means of a multicenter trial from 1981 to 1984. One hundred fifty-three cases were registered and 120 of them were evaluable. The overall response rate was 72.5% with 55 complete responses and 32 partial responses. Adverse effects were found in 34.8% of patients. This combination therapy of HCFU with radiation was therefore concluded to be useful for multidisciplinary treatment of head and neck cancer.