Related Experiment Video
Updated: Jul 30, 2025
Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Trends and characteristics of COVID-19 and cardiovascular disease related studies
Ao Cheng1, Honghao Ren1, Zeyao Ma1
1Laboratory Animal Centre, Xi'an Jiaotong University Health Science Centre, Xi'an, Shaanxi, China.
Insights
The new coronavirus (COVID-19) significantly impacts the cardiovascular system, increasing disease incidence. Research is shifting towards managing complications and preparing for new variants like Omicron.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic has caused widespread global health challenges.
- The full extent of cardiovascular damage associated with SARS-CoV-2 infection remains an area of active investigation.
- Understanding the relationship between cardiovascular diseases and COVID-19 is crucial for patient outcomes.
Purpose of the Study:
- To analyze the global research landscape on COVID-19 and cardiovascular disease.
- To identify trends in research focus and key contributors in this field.
- To understand the evolving research priorities concerning cardiovascular complications of SARS-CoV-2.
Main Methods:
- Bibliometric and visualization analysis of publications from the Web of Science database.
- Quantitative analysis of prolific authors, countries, journals, and institutions.
- Keyword co-occurrence analysis to track research theme evolution.
Main Results:
- SARS-CoV-2 demonstrates significant cardiovascular involvement, with a notable increase in cardiovascular disease incidence compared to baseline.
- Research keywords have evolved from initial focus on ACE2 and inflammation to myocarditis treatment and complication management.
- COVID-19 case numbers show seasonal patterns but are increasingly influenced by emerging mutant strains, necessitating continuous monitoring.
Conclusions:
- Future research should prioritize improving prognosis and reducing cardiovascular damage in COVID-19 patients.
- Timely detection and prevention of new SARS-CoV-2 mutant strains are critical public health tasks.
- Ongoing attention to the specific characteristics of variants like Omicron is essential for pandemic control.
Abstract:
Introduction: The new coronavirus has caused a pandemic that has infected hundreds of millions of people around the world since its outbreak. But the cardiovascular damage caused by the new coronavirus is unknown. We have analyzed the current global scenario and the general pattern of growth. After summarizing the known relationship between cardiovascular diseases and new coronary pneumonia, relevant articles are analyzed through bibliometrics and visualization. Methods: Following our pre-designed search strategy, we selected publications on COVID-19 and cardiovascular disease in the Web of Science database. In our relevant bibliometric visualization analysis, a total of 7,028 related articles in the WOS core database up to 20th October 2022 were summarized, and the most prolific authors, the most prolific countries, and the journals and institutions that published the most articles were summarized and quantitatively analyzed. Results: SARS-CoV-2 is more infectious than SARS-CoV-1 and has significant involvement in the cardiovascular system in addition to pulmonary manifestations, with a difference of 10.16% (20.26%/10.10%) in the incidence of cardiovascular diseases. The number of cases increases in winter and decreases slightly in summer with temperature changes, but the increase in cases tends to break out of seasonality across the region as mutant strains emerge. The co-occurrence analysis found that with the progress of the epidemic, the research keywords gradually shifted from ACE2 and inflammation to the treatment of myocarditis and complications, indicating that the research on the new crown epidemic has entered the stage of prevention and treatment of complications. Conclusion: When combined with the current global pandemic trend, how to improve prognosis and reduce human body damage could become a research focus. At the same time, timely detection, prevention, and discovery of new mutant strains have also become key tasks in the fight against the epidemic, and full preparations have been made to prevent the spread of the next wave of mutant strains, and still need to continue to pay attention to the differential performance of the variant "omicron."
Related Concept Videos
01:30Coronary Artery Disease I: Introduction
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
01:26Coronary Artery Disease II: Pathophysiology
01:27Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
01:30Coronary Artery Disease III: Clinical Manifestations