Related Experiment Video
Updated: Jul 30, 2025

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Risk factors for in-hospital death in 2,179 patients with acute aortic dissection
Yue Yuan1, Zhiyu Xia2, Lei Wang1
1Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Background:
This study aims to investigate the risk factors for in-hospital death in patients with acute aortic dissection (AAD) and to provide a straightforward prediction model to assist clinicians in determining the outcome of AAD patients.
Methods:
Retrospective analysis was carried out on 2,179 patients admitted for AAD from March 5, 1999 to April 20, 2018 in Wuhan Union Hospital, China. The risk factors were investigated with univariate and multivariable logistic regression analysis.
Results:
The patients were divided into two groups: Group A, 953patients (43.7%) with type A AAD; Group B, 1,226 patients (56.3%) with type B AAD. The overall in-hospital mortality rate was 20.3% (194/953) and 4% (50/1,226) in Group A and B respectively. The multivariable analysis included the variables that were statistically significant predictors of in-hospital death (P < 0.05). In Group A, hypotension (OR = 2.01, P = 0.001) and liver dysfunction (OR = 12.95, P < 0.001) were independent risk factors. Tachycardia (OR = 6.08, P < 0.001) and liver dysfunction (OR = 6.36, P < 0.05) were independent risk factors for Group B mortality. The risk factors of Group A were assigned a score equal to their coefficients, and the score of -0.5 was the best point of the risk prediction model. Based on this analysis, we derived a predictive model to help clinicians determine the prognosis of type A AAD patients.
Conclusions:
This study investigate the independent factors associated with in-hospital death in patients with type A or B aortic dissection, respectively. In addition, we develop the prediction of the prognosis for type A patients and assist clinicians in choosing treatment strategies.
Related Concept Videos
Aortic Regurgitation I: Introduction
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Aneurysm IV: Nursing Management
Aneurysm III: Interprofessional Care
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aneurysm I: Introduction

