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Staphylococcus aureus endocarditis. A review of 119 cases
Archives of Internal Medicine
|June 1, 1986
Summary
Staphylococcus aureus endocarditis is a serious condition with high mortality. This study found a concerning rise in hospital-acquired infections and a high rate of diagnosis at autopsy, highlighting diagnostic challenges.
Area of Science:
- Infectious Diseases
- Cardiology
- Epidemiology
Background:
- Staphylococcus aureus endocarditis poses a significant health risk.
- Understanding current trends in its incidence and characteristics is crucial for effective management.
Purpose of the Study:
- To review Staphylococcus aureus endocarditis cases in Denmark between 1976 and 1981.
- To analyze epidemiological features, clinical presentation, and outcomes.
Main Methods:
- Retrospective review of 119 Staphylococcus aureus endocarditis cases.
- Analysis of patient demographics, infection source, clinical signs, diagnostic methods, and mortality.
Main Results:
- The study included 119 patients (median age 63 years).
- Community-acquired infections were prevalent (62%), but hospital-acquired cases (38%) showed an increase.
- Diagnosis was often delayed, with 55% first identified at autopsy.
- The overall mortality rate was high at 71%.
Conclusions:
- Staphylococcus aureus endocarditis remains a critical illness with substantial mortality.
- Increased hospital-acquired infections and diagnostic delays contribute to poor outcomes.
- Age, hospital acquisition, heart failure, and embolism are associated with increased mortality.