A New Criterion for Shear Wave Elastometric Assessment Using Modulus of Stiffness Difference between Object and
I Yu Demin1, P I Rykhtik2, А E Spivak3
1Associate Professor, Department of Acoustics, Faculty of Radiophysics; National Research Lobachevsky State University of Nizhni Novgorod, 23 Prospekt Gagarina, Nizhny Novgorod, 603950, Russia.
Sovremennye Tekhnologii V Meditsine
|May 14, 2023
Summary
A new criterion, the modulus of stiffness difference, accurately compares tissue stiffness using ultrasound shear wave elastography. This method helps reduce operator dependence for reliable stiffness measurements.
Area of Science:
- Medical Imaging
- Biophysics
- Biomaterials
Background:
- Ultrasound shear wave elastography measures shear wave velocity to determine soft tissue stiffness.
- It enables point or two-dimensional elastography for comparative stiffness assessments.
Purpose of the Study:
- To develop a novel criterion for comparative stiffness assessment in shear wave elastometry.
- Introduce the modulus of stiffness difference between an object and its surrounding environment.
Main Methods:
- Performed point and two-dimensional shear wave elastography using commercial ultrasound scanners.
- Evaluated scanner accuracy on calibrated and uncalibrated phantoms with known and unknown stiffness.
- Assessed the influence of subjective factors and proposed techniques to mitigate them.
Main Results:
- The modulus of stiffness difference proved effective for comparative stiffness assessment across three ultrasound scanners.
- All scanners demonstrated high and comparable accuracy in determining inclusion stiffness within homogeneous media.
- Two-dimensional elastography results were influenced by control volume size and color scale settings, especially in heterogeneous objects.
Conclusions:
- The modulus of stiffness difference is a viable new criterion for comparative object assessment in shear wave elastometry.
- Minimizing operator dependence requires careful consideration of elastography method and other methodological factors.
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