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Related Concept Videos

Ethics in Research01:56

Ethics in Research

Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
Cloning of Dolly the Sheep01:08

Cloning of Dolly the Sheep

The first successfully cloned mammal was Dolly, a sheep, born on 5th July 1996 at Roslin Institute, Scotland. The cloned sheep was named after the American singer Dolly Parton. Dolly lived for seven years and died of respiratory complications, which is speculated to be due to the actual age of her DNA. Because the DNA in cloned cells belongs to an older individual,  the cloned individual’s life expectancy may be affected. Indeed, analysis of Dolly’s DNA revealed shorter telomeres than other...
Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...

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Related Experiment Video

Updated: Jul 25, 2026

A Standardized Protocol for Preference Testing to Assess Fish Welfare
07:29

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Published on: February 22, 2020

A Declaration of Helsinki for animals.

Vanessa Ashall1, David Morton2, Eddie Clutton3

  • 1Science and Technology Studies Unit (SATSU), Department of Sociology, Law and Sociology Building, University of York, York, UK.

Veterinary Anaesthesia and Analgesia
|May 14, 2023
PubMed
Summary

This study explores applying the Declaration of Helsinki

Keywords:
animalsethical best practiceharminformed consentriskveterinary clinical researchveterinary ethicsvulnerability

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Area of Science:

  • Veterinary Ethics
  • Medical Research Ethics

Background:

  • The Declaration of Helsinki provides an ethical framework for human medical research.
  • Clinical veterinary research (CVR) presents unique ethical challenges.
  • Existing veterinary regulations address CVR ethics to varying extents.

Purpose of the Study:

  • To assess the applicability of the Declaration of Helsinki's principles to CVR.
  • To identify ethical risks in CVR, including risk, harm, unproven interventions, vulnerability, and informed consent.
  • To propose a framework for international ethical best practice in CVR.

Main Methods:

  • Analysis of ethical principles from the Declaration of Helsinki.
  • Exploration of key ethical considerations in CVR.
  • Review of UK and EU veterinary regulatory approaches.

Main Results:

  • Ethical principles for human medical research can potentially be adapted for CVR.
  • CVR involves specific ethical risks related to patient welfare and consent.
  • Disagreements persist regarding the ethical appropriateness of certain CVR practices.

Conclusions:

  • A Declaration of Helsinki for Animals could establish international ethical standards for CVR.
  • Collaborative efforts are needed to address the benefits and challenges of implementing such a declaration.
  • Translating human research ethics principles to veterinary medicine requires careful consideration of animal patient interests.