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Updated: Jul 30, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Critical disease related to SARS-CoV-2 infection in children from the Amazon region: an observational study
Emmerson Carlos Franco de Farias1, Manoel Jaime Castro Pavão Júnior2, Susan C D de Sales2
1Pediatrics Department, Fundação Santa Casa de Misericórdia do Pará, Belem, Pará, Brazil emmersonfariasbrandynew@gmail.com.
Abstract:
This is a multicentre prospective cohort including critically ill children and adolescents, with confirmed critical disease related to SARS-CoV-2, admitted to three tertiary paediatric intensive care units in the Brazilian Amazon, between April 2020 and July 2022. 208 patients were included (median age was 3.5 years). The majority had malnutrition (62%) and comorbidities (60.6%). Mechanical ventilation support, cardiogenic shock and acute respiratory distress syndrome occurred in 47%, 30% and 34.1% of patients, respectively. There were 37 (18%) deaths. A poor outcome of severe COVID-19 and multisystem inflammatory syndrome in children was observed in children and adolescents from the Brazilian Amazon.
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