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Published on: April 21, 2019
Biologicals in IgE-mediated food allergy
Antonio Mutarelli1, Bruna Giavina-Bianchi2, Stefania Arasi3
1Federal University of Minas Gerais, Belo Horizonte, MG.
Purpose Of Review:
A better understanding of the most recent scientific literature in the use of biological therapy in the treatment of patients with IgE-mediated food allergy.
Recent Findings:
A systematic review and meta-analysis demonstrated safety and effectiveness of omalizumab in the treatment of food allergy. The findings support the potential use of omalizumab as a monotherapy or as an adjunct to oral immunotherapy in IgE-mediated cow's milk allergy. The potential use of other biologics in the management of food allergy is subject of speculation.
Summary:
Different biological therapies are under evaluation for food allergic patients. The advance in literature will guide for a personalized treatment in the near future. However, additional research is needed to better understand the best candidate for each treatment, the optimal dose and timing.
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