Medication Adherence and Its Associated Factors Among Outpatients with Heart Failure

Anan S Jarab1,2, Walid A Al-Qerem3, Hanan Walid Hamam1

  • 1Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, 22110, Jordan.

Insights

Poor medication adherence is common in heart failure patients. Interventions should target those with low education, on anticoagulants, or not on statins or ACEI/ARBs to improve outcomes.

Area of Science:

  • Cardiology
  • Pharmacology
  • Public Health

Background:

  • Medication adherence is crucial for effective heart failure (HF) management.
  • Poor adherence to HF medications significantly hinders desired health outcomes.
  • Identifying non-adherence factors is key to developing targeted interventions.

Purpose of the Study:

  • To assess medication adherence rates among heart failure patients in Jordan.
  • To identify factors associated with medication non-adherence in this population.

Main Methods:

  • A cross-sectional study was conducted in Jordanian outpatient cardiology clinics (August 2021-April 2022).
  • Data collected via medical records and questionnaires included socio-demographics, biomedical, disease, and medication characteristics.
  • Medication adherence was measured using the 4-item Morisky Medication Adherence Scale; multinomial logistic regression analyzed non-adherence factors.

Main Results:

  • 92.5% of 427 HF patients exhibited low to moderate medication adherence.
  • Higher education and absence of side effects correlated with moderate adherence.
  • Use of statins or ACEIs/ARBs was linked to higher adherence; non-use of anticoagulants also predicted better adherence.

Conclusions:

  • Low medication adherence is prevalent in Jordanian heart failure patients.
  • Intervention programs should focus on improving patient perception of medications.
  • Targeting interventions for patients with low education, on anticoagulants, or not on statins/ACEIs/ARBs is recommended.
Abstract

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