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Legionella-Induced Hepatitis: A Case Report.

Devesh Kumar1, Naisarg B Vanani1, Jared Dobbs1

  • 1Medicine, Medical College of Wisconsin, Wauwatosa, USA.

Cureus
|May 15, 2023
PubMed
Summary

Legionnaires disease, a severe pneumonia caused by Legionella pneumophila, can affect the liver. This case report highlights an unusual presentation of Legionella pneumonia with acute hepatitis.

Keywords:
acute kidney injuryaquatic systemscovid-19extrapulmonary manifestationsgram-negative bacillushepatitishyponatremialegionella pneumophilalegionnaire’s diseasepontiac fever

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Area of Science:

  • Infectious Diseases
  • Hepatology
  • Pulmonology

Background:

  • Legionnaires' disease is a severe pneumonia caused by the bacterium Legionella pneumophila.
  • Transmission occurs through inhaling contaminated water aerosols.
  • The disease typically presents as atypical community-acquired pneumonia, often with gastrointestinal symptoms like diarrhea.

Observation:

  • Hepatic and renal involvement are uncommon complications of Legionnaires' disease.
  • This report details a specific case of Legionella pneumonia.
  • The patient presented with concurrent acute hepatitis.

Findings:

  • The case demonstrates an unusual manifestation of Legionella pneumophila infection.
  • Acute hepatitis occurred alongside pneumonia in this patient.
  • This suggests a broader spectrum of organ involvement than typically observed.

Implications:

  • Clinicians should consider hepatic involvement in cases of severe Legionnaires' disease.
  • This case expands the understanding of Legionella's potential systemic effects.
  • Further research may elucidate the mechanisms behind Legionella-induced hepatitis.