A Comprehensive Review on MRI-based Knee Joint Segmentation and Analysis Techniques

Using magnetic resonance imaging (MRI) in osteoarthritis pathogenesis research has proven extremely beneficial. However, it is always challenging for both clinicians and researchers to detect morphological changes in knee joints from magnetic resonance (MR) imaging since the surrounding tissues produce identical signals in MR studies, making it difficult to distinguish between them. Segmenting the knee bone, articular cartilage and menisci from the MR images allows one to examine the complete volume of the bone, articular cartilage, and menisci. It can also be used to assess certain characteristics quantitatively. However, segmentation is a laborious and time-consuming operation that requires sufficient training to complete correctly. With the advancement of MRI technology and computational methods, researchers have developed several algorithms to automate the task of individual knee bone, articular cartilage and meniscus segmentation during the last two decades. This systematic review aims to present available fully and semi-automatic segmentation methods for knee bone, cartilage, and meniscus published in different scientific articles. This review provides a vivid description of the scientific advancements to clinicians and researchers in this field of image analysis and segmentation, which helps the development of novel automated methods for clinical applications. The review also contains the recently developed fully automated deep learning-based methods for segmentation, which not only provides better results compared to the conventional techniques but also open a new field of research in Medical Imaging.