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Published on: December 10, 2013
Respiratory Syncytial Virus Outbreak in Infants and Young Children during COVID-19 Pandemic in Taiwan
Hsin Chi1,2, Ching-Hu Chung2
1Department of Pediatrics, Mackay Memorial Hospital and Mackay Children's Hospital, Taipei 104, Taiwan.
Insights
Respiratory syncytial virus (RSV) causes significant hospitalizations in young children. This study reveals Taiwan
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Respiratory syncytial virus (RSV) poses a substantial health burden on infants and young children globally.
- RSV seasonality typically follows temperature and humidity patterns, but its specific patterns in subtropical regions like Taiwan require further investigation.
- The impact of the COVID-19 pandemic on RSV seasonality in Taiwan remained unclear.
Purpose of the Study:
- To investigate the seasonality of RSV hospitalizations in Taiwan.
- To analyze the monthly distribution of RSV hospitalizations.
- To assess the effects of the COVID-19 pandemic on RSV hospitalization patterns.
Main Methods:
- Utilized linked data from Taiwan's National Health Insurance Database and Death Registration Files.
- Analyzed birth data for infants aged 0-1 years and children aged 1-5 years.
- Examined RSV hospitalization (RSVH) rates over a 13-year period, including the COVID-19 pandemic era.
Main Results:
- RSVH rates in infants (0-1 year) were higher than in older children (1-5 years), ranging from 0.95% to 1.71% annually.
- Most years exhibited 2-3 RSV epidemic seasons in children aged 0-5 years.
- A significant RSVH surge occurred in autumn 2020 (September-December), with additional peaks observed in February-May and July-August.
Conclusions:
- Taiwan experiences year-round RSV hospitalization activity with distinct seasonal peaks.
- The COVID-19 pandemic was associated with a notable RSV outbreak in late 2020.
- Understanding RSV seasonality in subtropical regions is crucial for public health interventions.
Abstract:
Respiratory syncytial virus (RSV) is a major burden of disease in babies and young children, including hospitalizations and deaths. RSV is a seasonal disease that peaks when temperatures decrease in temperate zones and humidity increases in tropical regions. Existing research reveals that RSV hospitalization activity is year-round in Taiwan, which is a subtropical region with small peaks in spring and fall. The monthly distribution and COVID-19 pandemic impact were unclear. The aim of this study was to investigate Taiwan's RSV hospitalization seasonality and the COVID-19 pandemic effects. The National Health Insurance Database and Death Registration Files from the Center for Health and Welfare Data Science Center were connected to birth data for this study. RSV hospitalization (RSVH) in infants aged 0-1 years ranged from 0.9518% (2009) to 1.7113% (2020), substantially higher than in children aged 1-5. Most years had 2 or 3 RSV epidemic seasons in 0-5-year-olds over the 13-year follow-up. RSVH incidence was low until the autumn of 2020, when a major rise occurred after September and lasted until December 2020. We detected RSVH peaks in February-May and July-August. The 2020 RSV outbreak was found at the end of 2020.
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