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Ureterocystoplasty in Boys with Valve Bladder Syndrome-Is This Method Still up to Date?
Aybike Hofmann1, Alexandros Ioannou1,2, Pirmin Irenaeus Zöhrer1
1Department of Pediatric Urology in Cooperation with University Medical Center Regensburg, Hospital Barmherzige Brüder, Clinic St. Hedwig, 93049 Regensburg, Germany.
Insights
Ureterocytoplasty (UCP) effectively increases bladder capacity in boys with posterior urethral valves (PUV), allowing natural micturition and preserving kidney function. This safe surgical option improves long-term outcomes for pediatric patients.
Area of Science:
- Pediatric Urology
- Surgical Innovation
- Renal Function Preservation
Background:
- Posterior urethral valves (PUV) pose risks to renal function and long-term urinary tract health.
- Some boys with PUV require additional surgery to enhance bladder capacity and function.
- Ureterocytoplasty (UCP) is a surgical technique utilizing ureteral tissue for bladder augmentation.
Purpose of the Study:
- To evaluate the long-term efficacy and safety of ureterocytoplasty (UCP) in pediatric patients with posterior urethral valves (PUV).
- To assess the impact of UCP on bladder capacity, renal function, and spontaneous micturition in boys with PUV.
Main Methods:
- Retrospective analysis of 10 boys with PUV who underwent UCP between 2004 and 2019.
- Evaluation of pre- and postoperative data including kidney and bladder function, SWRD scores, and complications.
- Assessment of long-term follow-up data, including spontaneous micturition and need for further augmentation.
Main Results:
- UCP resulted in a mean 25% increase in age-adjusted bladder capacity.
- Eight out of ten boys achieved spontaneous micturition post-UCP.
- No severe hydronephrosis or need for conversion to intestinal augmentation was observed.
- The SWRD score showed a significant median decrease, indicating improved bladder-rectum coordination.
Conclusions:
- Ureterocytoplasty (UCP) is a safe and effective surgical option for improving bladder capacity in boys with posterior urethral valves (PUV).
- UCP can preserve or improve renal function and maintain the potential for natural micturition.
- This technique offers a viable alternative to intestinal augmentation for select pediatric patients with PUV.
Abstract:
Boys with valve bladder syndrome (PUV) require adequate treatment of the lower urinary tract to preserve renal function and improve long-term outcomes. In some patients, further surgery may be necessary to improve bladder capacity and function. Ureterocytoplasty (UCP) is usually carried out with a small segment of intestine or, alternatively, with a dilated ureter. Our aim was to evaluate the long-term outcomes after UCP in boys with PUV. UCP had been performed in 10 boys with PUV at our hospital (2004-2019). Pre- and postoperative data were evaluated in relation to kidney and bladder function, the SWRD score, additional surgery, complications, and long-term follow-up. The mean time between primary valve ablation and UCP was 3.5 years (SD ± 2.0). The median follow-up time was 64.5 months (IQR 36.0-97.25). The mean increase in age-adjusted bladder capacity was 25% (from 77% (SD ± 0.28) to 102% (SD ± 0.46)). Eight boys micturated spontaneously. Ultrasounds showed no severe hydronephrosis (grade 3-4). The SWRD score showed a median decrease from 4.5 (range 2-7) to 3.0 (range 1-5). No conversion of augmentation was required. UCP is a safe and effective approach to improve bladder capacity in boys with PUV. In addition, the possibility of micturating naturally is still maintained.
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