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Related Experiment Video

Updated: Jul 30, 2025

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Determining the Optimal Dosage of Corticosteroid Injection in Trigger Finger.

Jared Bookman1, Madeline Rocks2, Karen Noh3

  • 1NYU Langone Long Island School of Medicine, Mineola, NY, USA.

Hand (New York, N.Y.)
|May 16, 2023
PubMed
Summary

A 20-mg triamcinolone acetonide injection significantly improved trigger finger outcomes compared to 5-mg and 10-mg doses. This higher corticosteroid dose demonstrated greater clinical effectiveness at six months for trigger finger treatment.

Keywords:
anatomydiagnosishandpainresearch and health outcomesspecialtysurgerytendontreatment

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Area of Science:

  • Orthopedics
  • Hand Surgery
  • Musculoskeletal Disorders

Background:

  • Corticosteroid injection is a primary nonoperative treatment for trigger finger (stenosing tenosynovitis).
  • Optimal corticosteroid dosing for trigger finger injections lacks substantial evidence.
  • This study addresses the need for evidence-based dosing guidelines.

Purpose of the Study:

  • To compare the efficacy of three different dosages of triamcinolone acetonide for trigger finger treatment.
  • To determine the optimal corticosteroid dose for trigger finger injections.
  • To evaluate the impact of varying triamcinolone acetonide doses on patient outcomes.

Main Methods:

  • Prospective enrollment of patients diagnosed with trigger finger.
  • Treatment with triamcinolone acetonide (Kenalog) injections at 5 mg, 10 mg, or 20 mg.
  • Six-month longitudinal follow-up assessing clinical response, failure, Visual Analog Scale (VAS) pain, and Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) scores.

Main Results:

  • 163 trigger fingers across 146 patients were analyzed.
  • At 6 months, clinical effectiveness rates were 52% (5 mg), 62% (10 mg), and 79% (20 mg).
  • Significant improvements in VAS and QuickDASH scores were observed with the 20-mg dose compared to lower doses.

Conclusions:

  • A 20-mg dose of triamcinolone acetonide showed significantly higher clinical effectiveness at 6 months for trigger finger.
  • While pain and function scores improved, differences between dosage groups were not statistically significant.
  • The 20-mg dose represents a more effective option for trigger finger treatment based on clinical effectiveness.