[Capillary blood flow morphofunctional readjustments in northerners of different ages.]

Morphofunctional characteristics of capillary blood flow can be considered one of the most sensitive markers of ontogenetic desadaptive changes both within a local area of the capillary network and in the entire cardiovascular system. The study involved two hundred seventy-seven male northerners aged 18-66 to identify the age dynamics of the capillary bed morphofunctional characteristics. Subjects exhibited a reduction in diameters of arterial and transitional sections of the microcapillary bed testifying to a significant age dynamics from young men to the elderly. The remodeling coefficient increasingly came up in workable and elderly men, which indicated the risk of reducing in effectiveness of substances diffusion. We could see the average capillary length increase in this age vector and considered that as a compensatory growth of the contact surface of the vessel aimed at maintaining the necessary level of transcapillary exchange. We clearly observed microcirculatory changes with subjective age and considered them to be adaptive changes of microangioarchitectonics which may indicate the formation of a pattern characteristic of northerners' ontogenetic readjustments.