Related Experiment Video
Updated: Jul 30, 2025

A Procedure to Observe Context-induced Renewal of Pavlovian-conditioned Alcohol-seeking Behavior in Rats
Published on: September 19, 2014
A contextualized reinforcer pathology approach to addiction
Samuel F Acuff1, James MacKillop2,3, James G Murphy4
1Alpert Medical School, Brown University, Providence, RI USA.
Harmful drug use is linked to valuing immediate rewards over delayed ones and high drug demand. Environmental factors, like limited access to alternative reinforcers, significantly impact addiction risk.
Area of Science:
- Behavioral economics
- Addiction science
- Psychology
Background:
- Behavioral economic models explain addiction via overvaluation of immediate rewards (delay discounting) and high drug demand.
- These models focus on within-individual motivational processes.
- Learning theory highlights environmental factors, specifically the availability of alternative reinforcers.
Purpose of the Study:
- To integrate alternative reinforcers into behavioral economic models of addiction.
- To propose the contextualized reinforcer pathology model.
- To review empirical support for this integrated model.
Main Methods:
- Review of empirical literature across the translational spectrum.
- Integration of concepts from behavioral economics and learning theory.
- Conceptual analysis of addiction as a contextualized reinforcer pathology.
Main Results:
- The contextualized reinforcer pathology model provides a framework for understanding harmful drug use.
- Lack of alternative reinforcement is identified as a significant risk factor for addiction.
- The model helps explain increases in drug-related mortality and health disparities.
Conclusions:
- Integrating environmental factors, specifically alternative reinforcers, enhances behavioral economic accounts of addiction.
- The contextualized reinforcer pathology model offers a more comprehensive understanding of addiction.
- Addressing lack of alternative reinforcement may be key to ameliorating addiction and its disparities.
Related Concept Videos
Drug Abuse and Addiction: Pharmacological Phenomena
Operant Conditioning Intervention
In operant conditioning, behaviors that are...
Real-World Application of Classical Conditioning
Higher-order, or second-order, conditioning occurs when a neutral stimulus becomes associated with an already established conditioned stimulus through repeated pairings. For instance, if a dog has been...
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Classical Conditioning in Daily Life
John B. Watson and Rosalie Rayner famously demonstrated the development of fear through classical conditioning in their experiment with Little Albert. They paired the...
Drug Dependence

