Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Amygdalospinal projections in the cat.

B B Sandrew, D L Edwards, C E Poletti

    Brain Research
    |May 14, 1986
    PubMed
    Summary

    Researchers traced neural pathways from the spinal cord to the amygdala in cats. They identified specific amygdalospinal neurons in the central and medial amygdala nuclei, crucial for brain-spinal cord communication.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Systematic review and meta-analysis of the performance of clinical risk assessment instruments for screening for osteoporosis or low bone density.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2015
    Same author

    The effect of tendon vibration on motor unit activity, intermuscular coherence and force steadiness in the elbow flexors of males and females.

    Acta physiologica (Oxford, England)·2014
    Same author

    Performance of risk assessment instruments for predicting osteoporotic fracture risk: a systematic review.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2013
    Same author

    Effects of vicariant barriers, habitat stability, population isolation and environmental features on species divergence in the south-western Australian coastal reptile community.

    Molecular ecology·2012
    Same author

    Morphological differentiation correlates with ecological but not with genetic divergence in a Gehyra gecko.

    Journal of evolutionary biology·2012
    Same author

    Age- and sex-related differences for electromyography gaps during daily activity and a discrete task.

    Gait & posture·2011

    Area of Science:

    • Neuroscience
    • Spinal Cord Research
    • Amygdala Function

    Background:

    • The amygdala plays a key role in processing emotions and regulating autonomic responses.
    • Understanding the descending pathways from the amygdala to the spinal cord is essential for comprehending pain modulation and emotional regulation.
    • Previous research has suggested connections between the amygdala and the spinal cord, but the precise neuronal populations involved require further elucidation.

    Purpose of the Study:

    • To identify and characterize the specific neuronal populations in the amygdala that project to the spinal cord in cats.
    • To map the distribution and morphology of these amygdalospinal neurons.

    Main Methods:

    • Spinal cord injections of rhodamine-labeled fluorescent latex microspheres were performed in adult cats.
    • Retrograde neuronal tracing techniques were employed to identify neurons with projections to the injection site.
    • Microscopic analysis was used to visualize and characterize the labeled neurons within the amygdala.

    Main Results:

    • A dense, well-defined population of neurons was retrogradely labeled in the central nucleus of the amygdala.
    • A modest number of neurons in the medial nucleus of the amygdala were also labeled.
    • These amygdalospinal neurons were characterized as large cells with variable shapes and orientations.
    • The distribution of these neurons was bilateral, with a notable ipsilateral predominance.

    Conclusions:

    • The central nucleus of the amygdala is a major source of descending projections to the spinal cord in cats.
    • The medial nucleus also contributes to spinal cord innervation, albeit to a lesser extent.
    • These findings highlight the amygdala's role in modulating spinal cord activity and provide insights into the neuroanatomical basis of emotional and autonomic regulation via the amygdalospinal pathway.

    Related Experiment Videos